A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10101
Swiss-prot Accession numberQ25683 (Sequence in FASTA format)
DescriptionCrustacean hyperglycemic hormones precursor [Contains: CHH precursor-related peptide (CPRP); Crustacean hyperglycemic hormone (CHH)].
Source organismProcambarus clarkii (Red swamp crayfish)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Procambarus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityProduced by the medulla terminalis X-organ in the eyestalks and transported to the sinus gland where they are stored and released
Post translational modificationN/A
FunctionHormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction
Protein Length137 Amino acids
Molecular weight15264
References1   Yasuda-Kamatani Y., Yasuda A.; "Crustacean hyperglycemic hormone precursor from Procambarusclarkii."; Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
2   Kang W.; Submitted (MAR-1993) to the EMBL/GenBank/DDBJ databases.
3  PubMed abstract 7821776
Domain NameCrust_neurohorm  
Hormone NameCrustacean hyperglycemic hormone
Mature Hormone SequenceQVFDQACKGIYDRAIFKKLDRVCEDCYNLYRKPYVATTCRQNCYANSVFRQCLDDLLLIDVVDEYISGVQTV
Position of mature hormone in Pre-Hormone protein72 Residues from position (64-135)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10138
Swiss-prot Accession numberQ9TWW7 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone (PDH).
Source organismProcambarus clarkii (Red swamp crayfish)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Procambarus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionCauses the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas
Protein Length18 Amino acids
Molecular weight1942
References1  PubMed abstract 1823925
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSELINSILGLPKVMNEA
Position of mature hormone in Pre-Hormone protein18 Residues from position (1-18)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10652
Swiss-prot Accession numberP55848 (Sequence in FASTA format)
DescriptionMolt-inhibiting hormone (MIH).
Source organismProcambarus clarkii (Red swamp crayfish)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Procambarus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInhibits Y-organs where molting hormone (ecdysteroid) is secreted. A molting cycle is initiated when MIH secretion diminishes or stops
Protein Length75 Amino acids
Molecular weight8658
References1  PubMed abstract 8901124
Domain NameCrust_neurohorm  
Hormone NameMolt-inhibiting hormone
Mature Hormone SequenceRYVFEECPGVMGNRAVHGKVTRVCEDCYNVFRDTDVLAGCRKGCFSSEMFKLCLLAMERVEEFPDFKRWIGILNA
Position of mature hormone in Pre-Hormone protein75 Residues from position (1-75)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated