A database of hormones and their receptors |
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HMRbase accession number | 10101 |
Swiss-prot Accession number | Q25683 (Sequence in FASTA format) |
Description | Crustacean hyperglycemic hormones precursor [Contains: CHH precursor-related peptide (CPRP); Crustacean hyperglycemic hormone (CHH)]. |
Source organism | Procambarus clarkii (Red swamp crayfish) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Procambarus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. |
Tissue Specificity | Produced by the medulla terminalis X-organ in the eyestalks and transported to the sinus gland where they are stored and released |
Post translational modification | N/A |
Function | Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction |
Protein Length | 137 Amino acids |
Molecular weight | 15264 |
References | 1 Yasuda-Kamatani Y., Yasuda A.; "Crustacean hyperglycemic hormone precursor from Procambarusclarkii."; Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
2 Kang W.; Submitted (MAR-1993) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7821776 |
Domain Name | Crust_neurohorm |
Hormone Name | Crustacean hyperglycemic hormone |
Mature Hormone Sequence | QVFDQACKGIYDRAIFKKLDRVCEDCYNLYRKPYVATTCRQNCYANSVFRQCLDDLLLIDVVDEYISGVQTV |
Position of mature hormone in Pre-Hormone protein | 72 Residues from position (64-135) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10138 |
Swiss-prot Accession number | Q9TWW7 (Sequence in FASTA format) |
Description | Pigment-dispersing hormone (PDH). |
Source organism | Procambarus clarkii (Red swamp crayfish) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Procambarus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the arthropod PDH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas |
Protein Length | 18 Amino acids |
Molecular weight | 1942 |
References | 1 PubMed abstract 1823925 |
Domain Name | Pigment_DH |
Hormone Name | Pigment-dispersing hormone |
Mature Hormone Sequence | NSELINSILGLPKVMNEA |
Position of mature hormone in Pre-Hormone protein | 18 Residues from position (1-18) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10652 |
Swiss-prot Accession number | P55848 (Sequence in FASTA format) |
Description | Molt-inhibiting hormone (MIH). |
Source organism | Procambarus clarkii (Red swamp crayfish) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Procambarus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Inhibits Y-organs where molting hormone (ecdysteroid) is secreted. A molting cycle is initiated when MIH secretion diminishes or stops |
Protein Length | 75 Amino acids |
Molecular weight | 8658 |
References | 1 PubMed abstract 8901124 |
Domain Name | Crust_neurohorm |
Hormone Name | Molt-inhibiting hormone |
Mature Hormone Sequence | RYVFEECPGVMGNRAVHGKVTRVCEDCYNVFRDTDVLAGCRKGCFSSEMFKLCLLAMERVEEFPDFKRWIGILNA |
Position of mature hormone in Pre-Hormone protein | 75 Residues from position (1-75) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |